BioPREVAIL Innovation

Catalyzing New Solutions for Sustainable Laboratories

Focus: Innovation Accelerator

BioPREVAIL Innovation is the core of the BioPREVAIL ecosystem: the program that hosts our annual Innovation Challenges and supports the teams they surface. It exists to find, accelerate, and back bold interdisciplinary solutions that strengthen biosecurity.

Biosecurity is not contained by the walls of a laboratory. It depends on every activity along the pathogen value chain*: the collection and testing of samples in the field, their transportation, their handling in the laboratory, the disposal of infectious waste, and the management of bio-repositories. A weakness at any point along that chain is a weakness across all of it.

Each annual Innovation Challenge directs the efforts of scientists, engineers, technicians, entrepreneurs, and policymakers at a defined part of that chain. Our first challenge addressed the built environment of the laboratory. The challenges that follow reach beyond it, into the practices, processes, and systems that surround the laboratory and connect it to everything else.

We focus particularly on the points along the chain most exposed in resource-constrained and rapidly changing environments, where operational failure carries national, regional, and global consequences.

Rather than promoting innovation for its own sake, BioPREVAIL Innovation prioritizes solutions that are practical, scalable, context-responsive, and capable of strengthening biosecurity wherever along the chain the risk actually sits.

*Karlsson EA, Blacksell SD, Carroll D, Harper DR, Morzaria S, Claes F. We need a global framework for promoting safe handling of high consequence pathogens. BMJ. 2024;386:q1855. doi:10.1136/bmj.q1855. PMID: 39179287.

Innovation Challenge – The Full Chain

Areas of interest across the chain

01: Field collection and testing
02: Transportation
03: Laboratory handling
04: Waste disposal
05: Bio-repository management
Across the whole chain

How BioPREVAIL Innovation Challenges Work

Designed for impact

Each design challenge is built around concrete laboratory system problems identified through engagement with national experts, facility managers, and technical specialists.

Through intensive design sprints, innovators rapidly accelerate the development of technologies to address laboratory challenges. Teams receive structured mentorship, technical guidance, and targeted learning to strengthen feasibility and performance.

Solutions are created to work within the constraints, capacities, and infrastructure of the settings where they will be used.

Promising solutions progress through laboratory pilots across the BioPREVAIL network, generating real world evidence and enabling scale through partnerships.

Current Challenge

BioPREVAIL x CEPI Biosecurity Innovation Challenge

The BioPREVAIL × CEPI Biosecurity Innovation Challenge identifies and incubates solutions that keep laboratory biosafety and biosecurity strong under 100 Days Mission conditions — and that hold once the surge has passed. Delivered by the Global Health Security Fund through BioPREVAIL with CEPI, it culminates in a public showcase at the World Health Assembly in May 2027.

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Be Part of the Solution

Join us to strengthen sustainable laboratory systems. Collaboration across disciplines, sectors, and regions is not possible without you.